The Treatment of Chronic Intestinal Amœbiasis with the Alkaloids of Holarrhena Antidysenterica (Kurchi)

نویسندگان

  • Hugh W. Acton
  • R. N. Chopra
چکیده

Chopra and others (1927) have shown that the alkaloids of Holarrliena antidysenterica possess marked amcebicidal properties, and Ghosh and Ghosh (1928) have shown that the Indian species of H. antidysenterica contain, besides conessine, two other alkaloids which they named kurchicine and kurcliine, respectively. Ghosh and Bose (1932) isolated these alkaloids in pure form and showed that the alkaloid, kurchine, is characterised by having

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Study on the Preparation of an Efficient Extract of Kurchi (Holarrhena Antidysenterica)

course of a few years. The therapeutic value of the drug has been found to be due mainly to its contained alkaloids whose actions are as potent as those of emetine, without producing the toxic effect of the latter. The researches of Acton and Chopra have definitely established that the alkaloids in kurchi have a similar amcebicidal effect to that of emetine. Again, some other workers (Henry and...

متن کامل

Antibacterial and antidiarrhoeal effects of alkaloids of Holarrhena antidysenterica WALL.

The alkaloids from the ethanolic extract of H. antidysenterica seeds were evaluated for their antibacterial activity against clinical isolates of enteropathogenic Escherichia coli (EPEC) in vitro, and their antidiarrhoeal activity on castor oil-induced diarrhoea in rats, in vivo. The plasmid DNA, whole cell lysate and outer membrane protein profile of a clinical isolate of EPEC was determined i...

متن کامل

Thai ethnomedicinal plants as resistant modifying agents for combating Acinetobacter baumannii infections

BACKGROUND Acinetobacter baumannii is well-recognized as an important nosocomial pathogen, however, due to their intrinsic resistance to several antibiotics, treatment options are limited. Synergistic effects between antibiotics and medicinal plants, particularly their active components, have intensively been studied as alternative approaches. METHODS Fifty-one ethanol extracts obtained from ...

متن کامل

Computation of In Vivo Antidiabetic Activity of Holarrhena Antidysenterica Seeds Extracts in Streptozotocin-Induced Diabetic Rats

Medicinal plants have curative properties due to the presence of various complex chemical compositions, which are found as secondary plant metabolites in one or more parts of the plant. The aim of this study was to compute the antidiabetic activity of Holarrhena antidysenterica   seeds extract in streptozotocin-induced diabetic rats. The experimental protocol designed as animals were divided i...

متن کامل

Effect of Methanolic Extract of Holarrhena Antidysenterica Bark against Experimentally Induced Inflammatory Bowel Disease in Rats

It has been demonstrated that Holarrhena antidysenterica Wall. (Apocynaceae) is useful as an adjunctive therapy for Inflammatory bowel disease (IBD). However, its effect on ulcerative colitis has not been investigated. In the present study, Holarrhena antidysenterica was tested for 2, 4 dinitro benzene sulfonic acid (DNBS) induced colitis, and antioxidant activity was evaluated to clarify its p...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 68  شماره 

صفحات  -

تاریخ انتشار 2016